In Vitro Potency Studies
ViruSure can support you to develop and validate a customized cell-based potency assay to measure the biological activity of your biopharmaceutical product. Potency assays are available for a wide range of products such as antibodies, cytokines, hormones and vaccines.
Potency Assays on Biopharmaceutical Products
Anti-viral assays (AVA)
Cell proliferation assays
Antibody-dependent cellular cytotoxicity assays (ADCC)
Complement-dependent cytotoxicity assays (CDC)
Reporter gene assays
MHC-I up-regulation assays
Induced lymphocyte assays (ILA)
Human Artificial Lymph Node (HuALN) model
Dendritic cell (DC) assays
T cell assays
Cytotoxicity and apoptosis assays
Cell cycle monitoring
Target specific CBAs
The use of animals for in vivo potency assays is diminishing, given disadvantages associated with cost, low throughput, practical, and especially ethical considerations.