Tissue Engineering

Tissue engineering is an emerging multidisciplinary ATMP field that aims to repair, regenerate or replace human tissue. It pursues a multi-faceted approach combining scaffolds with cell- and animalderived products aiming to the treatment of tissue defects and lesions.

At first, the appropriate cells are required. The cells can be sourced from either the patient (autologous), a donor (allogeneic), or another species (xenogeneic). The scaffold, or matrix, serves as a biomaterial framework to support cell migration into the defect from surrounding tissues. The scaffold can be natural, synthetic, or a combination of materials. In addition, there could be regulator signals such as growth factors or other biomechanical/biochemical signals that induce tissue formation or modifications of cell characteristics.

For this combined therapy ViruSure offers a complete range of services covering the biosafety of both the scaffolding material, cell product and associated growth factors. For instance, for animalderived scaffolds/medical devices ViruSure can check prion or virus safety and removal during the manufacturing process via clearance studies.

ViruSure’s expertise will ensure safety of tissue engineering products and medical devices.